Acetyl Hexamethyl Tetralin (AHTN)
INCI: ACETYL HEXAMETHYL TETRALIN
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Acetyl Hexamethyl Tetralin (AHTN). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 15 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=10 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOEL | 10 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 1.5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 ppm | oral | rat | oral | REACH |
Expert Verdict
Prohibited in EU due to scheduled re-evaluation for potential endocrine disruption and environmental persistence (bioaccumulative, BCF 597); classified as not genotoxic, not carcinogenic, and no warranted neurotoxicity classification per CLP. Permitted in US per RIFM Expert Panel.
Regulatory Flags
Frequently Asked Questions
Is Acetyl Hexamethyl Tetralin (AHTN) safe in cosmetics?
Prohibited in EU due to scheduled re-evaluation for potential endocrine disruption and environmental persistence (bioaccumulative, BCF 597); classified as not genotoxic, not carcinogenic, and no warranted neurotoxicity classification per CLP. Permitted in US per RIFM Expert Panel. The EU classifies Acetyl Hexamethyl Tetralin (AHTN) as "prohibited". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is Acetyl Hexamethyl Tetralin (AHTN) allowed in the EU?
Acetyl Hexamethyl Tetralin (AHTN) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Hexamethyl Tetralin (AHTN) do in cosmetics?
Acetyl Hexamethyl Tetralin (AHTN) functions as: Masking agent (polycyclic musk fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 1506-02-1.
What is the Margin of Safety for Acetyl Hexamethyl Tetralin (AHTN)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acetyl Hexamethyl Tetralin (AHTN)?
The NOAEL (No Observed Adverse Effect Level) for Acetyl Hexamethyl Tetralin (AHTN) is 15 mg/kg bw/day based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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