Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Allyl Isovalerate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 250 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 31 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 62 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | mouse | Subchronic | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Delayed irritant potential from allyl alcohol release; quality control of free allyl alcohol level is critical
Regulatory Flags
Frequently Asked Questions
Is Allyl Isovalerate safe in cosmetics?
Delayed irritant potential from allyl alcohol release; quality control of free allyl alcohol level is critical The EU classifies Allyl Isovalerate as "permitted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.
Is Allyl Isovalerate allowed in the EU?
Allyl Isovalerate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Allyl Isovalerate do in cosmetics?
Allyl Isovalerate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 2835-39-4.
What is the Margin of Safety for Allyl Isovalerate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Allyl Isovalerate?
The NOAEL (No Observed Adverse Effect Level) for Allyl Isovalerate is 250 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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