Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Alpha-Terpinene. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 60 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
Expert Verdict
Auto-oxidation is the primary concern. Must control peroxide values and store under nitrogen or antioxidant protection, as oxidized terpinene forms are potent sensitizers. EU places peroxide limits on similar terpene-rich essential oils in Annex III.
Regulatory Flags
Frequently Asked Questions
Is Alpha-Terpinene safe in cosmetics?
Auto-oxidation is the primary concern. Must control peroxide values and store under nitrogen or antioxidant protection, as oxidized terpinene forms are potent sensitizers. EU places peroxide limits on similar terpene-rich essential oils in Annex III. The EU classifies Alpha-Terpinene as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Alpha-Terpinene allowed in the EU?
Alpha-Terpinene EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Alpha-Terpinene do in cosmetics?
Alpha-Terpinene functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 99-86-5.
What is the Margin of Safety for Alpha-Terpinene?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Alpha-Terpinene?
The NOAEL (No Observed Adverse Effect Level) for Alpha-Terpinene is 60 mg/kg bw/day based on a Developmental study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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