2-Methyl-3-Buten-2-Ol
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for 2-Methyl-3-Buten-2-Ol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1250 mg/kg bw/day | oral | mouse | Special Toxicology Study | COSMOS_DB |
| NOAEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 150 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | ca.50 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Fragrance ingredient with low acute toxicity; flammable liquid requiring appropriate handling and concentration controls.
Regulatory Flags
Frequently Asked Questions
Is 2-Methyl-3-Buten-2-Ol safe in cosmetics?
Fragrance ingredient with low acute toxicity; flammable liquid requiring appropriate handling and concentration controls. The EU classifies 2-Methyl-3-Buten-2-Ol as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is 2-Methyl-3-Buten-2-Ol allowed in the EU?
2-Methyl-3-Buten-2-Ol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Methyl-3-Buten-2-Ol do in cosmetics?
2-Methyl-3-Buten-2-Ol functions as: Flavouring and nutrient; Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 115-18-4.
What is the Margin of Safety for 2-Methyl-3-Buten-2-Ol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Methyl-3-Buten-2-Ol?
The NOAEL (No Observed Adverse Effect Level) for 2-Methyl-3-Buten-2-Ol is 1250 mg/kg bw/day based on a Special Toxicology Study study via oral route in mouse. A total of 4 study endpoints are available. Source: COSMOS_DB.
Is 2-Methyl-3-Buten-2-Ol classified as hazardous under GHS?
2-Methyl-3-Buten-2-Ol carries a GHS signal word of "DANGER". Hazard statements: Highly flammable liquid and vapour Harmful if swallowed Causes eye irritation. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
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Related Ingredients
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