Is Alpha-Santalol safe in cosmetics?
Alpha-Santalol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Alpha-Santalol
Also known as: 2-Penten-1-ol, 5-[(1R,3R,6S)-2,3-dimethyltricyclo[2.2.1.02,6]hept-3-yl]-2-methyl-, (2Z)-, 2-Penten-1-ol, 5-(2,3-dimethyltricyclo[2.2.1.02,6]hept-3-yl)-2-methyl-, [R(Z)]-, Tricyclo[2.2.1.02,6]heptane, 2-penten-1-ol deriv., Sandal, cis-a-Santalol (+15 more)
INCI: ALPHA-SANTALOL
Alpha-Santalol (CAS 115-71-9) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 115-71-9 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(Z)-5-[(1S,3R,6R)-2,3-dimethyl-3-tricyclo[2.2.1.02,6]heptanyl]-2-methylpent-2-en-1-ol
InChIKey
PDEQKAVEYSOLJX-RQGDDBKYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted; sandalwood oil is FEMA GRAS for food flavoring; cosmetic use permitted under general fragrance provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Alpha-Santalol.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Regulatory (2)
JECFA Evaluation
ARGEOL | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/41 | FAS 50-JECFA 59/173
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ARHEOL | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/41 | FAS 50-JECFA 59/173
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Alpha-Santalol.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
2-Penten-1-ol, 5-[(1R,3R,6S)-2,3-dimethyltricyclo[2.2.1.02,6]hept-3-yl]-2-methyl-, (2Z)-
2-Penten-1-ol, 5-(2,3-dimethyltricyclo[2.2.1.02,6]hept-3-yl)-2-methyl-, [R(Z)]-
Tricyclo[2.2.1.02,6]heptane, 2-penten-1-ol deriv.
Sandal
cis-a-Santalol
C(Z)-a-Santalol
(+)-a-Santalol
(+)-(Z)-a-Santalol
d-a-Santalol
α-Santalol
5-(2,3-Dimethyltricyclo(2.2.1.0(2,6))hept-3-yl)-2-methyl-2-penten-1-ol
5-(2,3-Dimethyltricyclo(2.2.1.02,6)hept-3-yl)-2-methyl-2-penten-1-ol stereoisomer
EINECS 204-102-8
2-Penten-1-ol, 5-(2,3-dimethyltricyclo(2.2.1.02,6)hept-3-yl)-2-methyl-, stereoisomer
2-Penten-1-ol, 5-(2,3-dimethyltricyclo(2.2.1.0(sup 2,6))hept-3-yl)-2-methyl
cis-alpha-Santalol
Santalol a
d-alpha-Santalol
(Z)-alpha-Santalol
UNII-15X09F2755
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Cleaning products and household care - air freshener; Europe
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL512210
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
SANTALOL, ALPHA
Food Category
flavoring
Frequently Asked Questions
Is Alpha-Santalol allowed in the EU?
Alpha-Santalol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Alpha-Santalol do in cosmetics?
Alpha-Santalol functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 115-71-9.
Is Alpha-Santalol used outside cosmetics?
Alpha-Santalol also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Alpha-Santalol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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