Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Aminoethyl Propanediol (AEPD). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Secondary amine with nitrosamine formation risk; impurity must be controlled and finished product must comply with nitrosamine limits (<50 µg/kg); related compound AMP is restricted under Annex III, warranting equivalent caution for AEPD.
Frequently Asked Questions
Is Aminoethyl Propanediol (AEPD) safe in cosmetics?
Secondary amine with nitrosamine formation risk; impurity must be controlled and finished product must comply with nitrosamine limits (<50 µg/kg); related compound AMP is restricted under Annex III, warranting equivalent caution for AEPD. The EU classifies Aminoethyl Propanediol (AEPD) as "restricted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Aminoethyl Propanediol (AEPD) allowed in the EU?
Aminoethyl Propanediol (AEPD) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Aminoethyl Propanediol (AEPD) do in cosmetics?
Aminoethyl Propanediol (AEPD) functions as: Buffering agent, pH adjuster. It is classified as a cosmetic ingredient in our database. CAS number: 115-70-8.
What is the Margin of Safety for Aminoethyl Propanediol (AEPD)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Aminoethyl Propanediol (AEPD)?
The NOAEL (No Observed Adverse Effect Level) for Aminoethyl Propanediol (AEPD) is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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