Aminopropanediol

INCI: AMINOMETHYL PROPANEDIOL

CAS Number
115-69-5 (2-amino-2-methyl-1,3-propanediol, also known as AMPD)
Function
Buffering and pH adjustment; fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed and concluded safe in present practices of use and concentration. Should not be formulated with N-nitrosating agents due to potential secondary amine impurities.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primary amine not a direct substrate for N-nitrosation but may contain secondary amine impurities; must not be combined with N-nitrosating agents.

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Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Aminopropanediol safe in cosmetics?

Primary amine not a direct substrate for N-nitrosation but may contain secondary amine impurities; must not be combined with N-nitrosating agents. The EU classifies Aminopropanediol as "permitted". Safety rating: GOOD.

Is Aminopropanediol allowed in the EU?

Aminopropanediol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aminopropanediol do in cosmetics?

Aminopropanediol functions as: Buffering and pH adjustment; fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 115-69-5 (2-amino-2-methyl-1,3-propanediol, also known as AMPD).

What is the Margin of Safety for Aminopropanediol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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