Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
9 study endpoints found for Anisaldehyde (p-Methoxybenzaldehyde). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 100 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 20 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 ppm | oral | rat | oral | REACH |
| NOAEL | 10000 ppm | oral | rat | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 10000 ppm | oral | rat | oral | REACH |
Expert Verdict
Mild skin/eye irritant at high concentrations; ensure oxidative stability as aldehydes can form peroxides on storage; potential cross-reactivity in fragrance-sensitive individuals though not a primary concern
Regulatory Flags
Frequently Asked Questions
Is Anisaldehyde (p-Methoxybenzaldehyde) safe in cosmetics?
Mild skin/eye irritant at high concentrations; ensure oxidative stability as aldehydes can form peroxides on storage; potential cross-reactivity in fragrance-sensitive individuals though not a primary concern The EU classifies Anisaldehyde (p-Methoxybenzaldehyde) as "permitted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.
Is Anisaldehyde (p-Methoxybenzaldehyde) allowed in the EU?
Anisaldehyde (p-Methoxybenzaldehyde) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Anisaldehyde (p-Methoxybenzaldehyde) do in cosmetics?
Anisaldehyde (p-Methoxybenzaldehyde) functions as: Perfuming, Flavoring. It is classified as a cosmetic ingredient in our database. CAS number: 123-11-5.
What is the Margin of Safety for Anisaldehyde (p-Methoxybenzaldehyde)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Anisaldehyde (p-Methoxybenzaldehyde)?
The NOAEL (No Observed Adverse Effect Level) for Anisaldehyde (p-Methoxybenzaldehyde) is 500 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 9 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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