Moderate Colorant Dermal Penetration

Asiatic Acid — Structured Cosmetic Ingredient

INCI: ASIATIC ACID

CAS Number
464-92-6
Function
Colorant
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes OTC drug. No specific restrictions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Asiatic Acid — Structured Cosmetic Ingredient, relevant to systemic exposure and MoS calculations.

Absorption %
4-10%
Penetration Level
stratum-corneum
Penetration Depth
stratum corneum/epidermis
Molecular Weight
488.7 Da
Log P
5.5
Systemic Absorption
minimal
Topical Bioavailability
2-8%
Safety Margin Factor
low
Vehicle Dependent
Yes — absorption varies by formulation

Source: Molecules 2012

Expert Verdict

Insufficient safety data available for Asiatic Acid; further assessment recommended.

⚠️
Concern Level: Moderate

Regulatory Flags

Allergen

Frequently Asked Questions

Is Asiatic Acid — Structured Cosmetic Ingredient safe in cosmetics?

Insufficient safety data available for Asiatic Acid; further assessment recommended. The EU classifies Asiatic Acid — Structured Cosmetic Ingredient as "permitted". Safety rating: MODERATE.

Is Asiatic Acid — Structured Cosmetic Ingredient allowed in the EU?

Asiatic Acid — Structured Cosmetic Ingredient EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Asiatic Acid — Structured Cosmetic Ingredient do in cosmetics?

Asiatic Acid — Structured Cosmetic Ingredient functions as: Colorant. It is classified as a Colorant in our database. CAS number: 464-92-6.

What is the Margin of Safety for Asiatic Acid — Structured Cosmetic Ingredient?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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