Excellent Colorant

CI 77492 (Yellow Iron Oxide)

INCI: CI 77492

CAS Number
51274-00-1
Function
Colorant
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Listed under 21 CFR 73.2250. Exempt from batch certification. Approved for use in externally applied cosmetics including the eye area. FDA requires synthetic-grade (not mined) iron oxides to avoid heavy metal contamination. Heavy metal impurity limits apply.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Yellow iron oxide is permitted in the EU (Annex IV Entry 136, Category 1) with no concentration limit beyond GMP and purity criteria, and in the US under 21 CFR 73.2250 exempt from batch certification for externally applied cosmetics including eye area. CIR evaluated as safe up to 40% in leave-on, 50% in rinse-off, and 78% in other products. One of the safest cosmetic colorants with negligible dermal absorption (~0.01%), zero sensitization potential, and approval across all major jurisdictions.

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Concern Level: None

Regulatory Flags

eu-annex-iv fda-color-additive-exempt iarc-group-3 cosmos-compliant heavy-metal-limits-apply eye-area-approved nanoparticle-distinction-note eu_children_restricted ifra_fragrance eu_cosing_listed

Frequently Asked Questions

Is CI 77492 (Yellow Iron Oxide) safe in cosmetics?

Yellow iron oxide is permitted in the EU (Annex IV Entry 136, Category 1) with no concentration limit beyond GMP and purity criteria, and in the US under 21 CFR 73.2250 exempt from batch certification for externally applied cosmetics including eye area. CIR evaluated as safe up to 40% in leave-on, 50% in rinse-off, and 78% in other products. One of the safest cosmetic colorants with negligible dermal absorption (~0.01%), zero sensitization potential, and approval across all major jurisdictions. The EU classifies CI 77492 (Yellow Iron Oxide) as "permitted". Safety rating: EXCELLENT.

Is CI 77492 (Yellow Iron Oxide) allowed in the EU?

CI 77492 (Yellow Iron Oxide) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 77492 (Yellow Iron Oxide) do in cosmetics?

CI 77492 (Yellow Iron Oxide) functions as: Colorant. It is classified as a Colorant in our database. CAS number: 51274-00-1.

What is the Margin of Safety for CI 77492 (Yellow Iron Oxide)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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