Is Azulene safe in cosmetics?
Azulene has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by cir.
Azulene
Also known as: Azunamic, Bicyclo(5.3.0)decapentaene, Bicyclo(5.3.0)-1,3,5,7,9-decapentaene, Bicyclo(5.3.0)-deca-2,4,6,8,10-pentaene, EINECS 205-993-6 (+2 more)
INCI: AZULENE
Azulene (CAS 275-51-4) is a cosmetic cosmetic ingredient functioning as Insufficient Data. EU Regulation 1223/2009 status: permitted, max 10%; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 275-51-4 →
Auto-generated CPSR Part A draft with source citations
Function
Insufficient Data
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
EU Max Conc.
10%
US US Status
permitted
US Notes
Insufficient data to support safety for cosmetic use (1999 Final Report).
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Azulene.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
Verdict: unknown
Additional Ingredient Properties
4 property records from structured ingredient metadata.
acne
{"cas_number": "275-51-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "5-15", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
pediatric_safety
{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "0.5", "adult_max_concentration_pct": "0.5", "pediatric_dermal_absorption_factor": "normal", "diaper_area_safe": "yes", "pediatric_allergy_prevalence": "low", "banned_in_children_products_eu": "no", "banned…
sensory
{"silky": "oily", "smooth, glides easily": "smooth, soothing", "dry-touch, non-greasy": "calm, blue-tint", "instant": "moderate", "low": "low", "w/o": "w/o", "very-high": "high", "no": "no", "yes": "no", "1.40": "0.90", "transparent": "transparent", "colorless": "deep-blue", "excellent": "good", "light": "light", "synthetic": "botanical"}
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "acceptable", "sensitive_skin": "recommended", "combination_skin": "acceptable", "normal_skin": "acceptable", "acne_prone": "acceptable", "rosacea": "recommended", "eczema": "recommended", "hyperpigmentation": "acceptable", "aging_mature": "acceptable", "dehydrated": "acceptable", "skin_benefit_primary": "soothing", "skin_benefit_secondary": "anti-inflammato…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Humectant
Softener and conditioner
Regulatory List Membership (2)
EU Regulated in Personal Care
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Azulene.
Known Synonyms
Azunamic
Bicyclo(5.3.0)decapentaene
Bicyclo(5.3.0)-1,3,5,7,9-decapentaene
Bicyclo(5.3.0)-deca-2,4,6,8,10-pentaene
EINECS 205-993-6
UNII-82R6M9MGLP
Azulen
Chemical Function
Softener and conditioner
Humectant
Fragrance
Regulatory Lists
Europe; Personal care
Cleaning products and household care - air freshener; Europe
air; Cleaning products and household care - air freshener; detected; emissions; Europe
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3272628
Adverse Event Associations
2
Frequently Asked Questions
Is Azulene allowed in the EU?
Azulene EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.
What does Azulene do in cosmetics?
Azulene functions as: Insufficient Data. It is classified as a cosmetic ingredient in our database. CAS number: 275-51-4.
Is Azulene used outside cosmetics?
Azulene also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Azulene compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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