Is Bifidobacterium Ferment Lysate safe in cosmetics?
Bifidobacterium Ferment Lysate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Bifidobacterium Ferment Lysate
INCI: BIFIDA FERMENT LYSATE
Bifidobacterium Ferment Lysate (CAS 96507-89-0) is a cosmetic cosmetic ingredient functioning as Skin conditioning (maintains skin in good condition); antioxidant (DPPH, ABTS,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 96507-89-0 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning (maintains skin in good condition); antioxidant (DPPH, ABTS, hydroxyl and superoxide radical scavenging); anti-inflammatory (reduces vasodilation, edema, mast cell degranulation, TNF-alpha release); skin barrier reinforcement (upregulates FLG, LOR, IVL, TGM1, AQP3, CAMP, hBD-2 genes)
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA-specific restriction; regulated as a cosmetic ingredient under FD&C Act. Not an OTC drug. No GRAS designation required for topical cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bifidobacterium Ferment Lysate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "…
anti_aging
{"anti_aging_claim": "barrier-repair, anti-wrinkle", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytothera…
anti_pollution
{"cas_number": "96507-89-0", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement/microbiome", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF…
baby_pediatric
{"cas_number": "CAS-FUNC-43", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Probiotic/postbiotic - emerging baby care", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_conc…
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "150", "estimated_cost_per_kg_usd_high": "280", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Korea/Japan", "bulk_discount_threshold_kg": "5", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Saccharo…
deodorant
{"cas_number": "96507-89-0", "ingredient_class": "postbiotic_deodorant", "mechanism_of_action": "microbiome_modulation", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "45-65", "bacteriostatic": "no", "bactericidal": "no", "target_bacteria": "promotes beneficial", "microbiome_impact": "prebiotic", "axillary_microbiome_effect": "varies…
depigmentation
{"cas_number": "formulation", "ingredient_class": "keratinocyte_turnover_enhancer", "primary_mechanism_of_action": "Fermentation metabolites provide gentle brightening and barrier support", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduc…
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "14-28", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "palm_…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Bifidobacterium Ferment Lysate.
Regulatory Flags
probiotic-derived
biotechnology-origin
skin-barrier-support
anti-inflammatory
ferment-lysate
k-beauty-staple
ewg-low-hazard
Chemical Function
Softener and conditioner
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Bifidobacterium Ferment Lysate allowed in the EU?
Bifidobacterium Ferment Lysate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bifidobacterium Ferment Lysate do in cosmetics?
Bifidobacterium Ferment Lysate functions as: Skin conditioning (maintains skin in good condition); antioxidant (DPPH, ABTS, hydroxyl and superoxide radical scavenging); anti-inflammatory (reduces vasodilation, edema, mast cell degranulation, TNF-alpha release); skin barrier reinforcement (upregulates FLG, LOR, IVL, TGM1, AQP3, CAMP, hBD-2 genes). It is classified as a cosmetic ingredient in our database. CAS number: 96507-89-0.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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