Bis-Hydroxypropyl Dimethicone

CAS Number
Requires verification — closely related Bis-Hydroxyethoxypropyl Dimethicone is CAS 222416-17-3 ; the hydroxypropyl variant may differ.
Function
Softener and conditioner
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Covered under CIR's Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers — concluded safe as used in cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Minimal concerns. Standard cyclotetrasiloxane (D4)/cyclopentasiloxane (D5) residual testing may apply depending on manufacturing process.

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Concern Level: Low

Frequently Asked Questions

Is Bis-Hydroxypropyl Dimethicone safe in cosmetics?

Minimal concerns. Standard cyclotetrasiloxane (D4)/cyclopentasiloxane (D5) residual testing may apply depending on manufacturing process. The EU classifies Bis-Hydroxypropyl Dimethicone as "permitted". Safety rating: EXCELLENT.

Is Bis-Hydroxypropyl Dimethicone allowed in the EU?

Bis-Hydroxypropyl Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-Hydroxypropyl Dimethicone do in cosmetics?

Bis-Hydroxypropyl Dimethicone functions as: Softener and conditioner. It is classified as a cosmetic ingredient in our database. CAS number: Requires verification — closely related Bis-Hydroxyethoxypropyl Dimethicone is CAS 222416-17-3 ; the hydroxypropyl variant may differ..

What is the Margin of Safety for Bis-Hydroxypropyl Dimethicone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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