Good Cosmetic Ingredient NOAEL Data

Butyl Ethyl Propanediol

INCI: BUTYL ETHYL PROPANEDIOL

CAS Number
115-84-4
Function
Humectant, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Adequate โ€” supported by alkane diols class assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Butyl Ethyl Propanediol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 15 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

No significant safety concerns. Widely used humectant and skin conditioning ingredient with established safety profile.

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Concern Level: Low

Frequently Asked Questions

Is Butyl Ethyl Propanediol safe in cosmetics?

No significant safety concerns. Widely used humectant and skin conditioning ingredient with established safety profile. The EU classifies Butyl Ethyl Propanediol as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Butyl Ethyl Propanediol allowed in the EU?

Butyl Ethyl Propanediol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Butyl Ethyl Propanediol do in cosmetics?

Butyl Ethyl Propanediol functions as: Humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 115-84-4.

What is the Margin of Safety for Butyl Ethyl Propanediol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Butyl Ethyl Propanediol?

The NOAEL (No Observed Adverse Effect Level) for Butyl Ethyl Propanediol is 15 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. Source: COSMOS_DB.

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