Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Butyl Methacrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 120 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 602 ppm | 1991 | rat | inhalation | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Butyl methacrylate is a film-forming monomer permitted in nail products with the critical restriction that direct skin contact must be avoided to maintain safety.
Regulatory Flags
Frequently Asked Questions
Is Butyl Methacrylate safe in cosmetics?
Butyl methacrylate is a film-forming monomer permitted in nail products with the critical restriction that direct skin contact must be avoided to maintain safety. The EU classifies Butyl Methacrylate as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Butyl Methacrylate allowed in the EU?
Butyl Methacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Butyl Methacrylate do in cosmetics?
Butyl Methacrylate functions as: Film former in nail products; monomer in nail coating systems. It is classified as a cosmetic ingredient in our database. CAS number: 97-88-1.
What is the Margin of Safety for Butyl Methacrylate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Butyl Methacrylate?
The NOAEL (No Observed Adverse Effect Level) for Butyl Methacrylate is 120 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Is Butyl Methacrylate classified as hazardous under GHS?
Butyl Methacrylate carries a GHS signal word of "WARNING". Hazard statements: Flammable liquid and vapour Causes skin and eye irritation May cause an allergic skin reaction May cause respiratory irritation May be harmful if swallowed and enters airways Harmful to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
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Related Ingredients
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