Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Calcium Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| dose_tested | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 1500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | >=3472.02 other | oral | - | oral | REACH |
| NOAEL | >=0.048 other | oral | - | oral | REACH |
| NOAEL | >=20.25 other | oral | - | oral | REACH |
| NOAEL | >=0.0096 other | oral | - | oral | REACH |
| NOAEL | >=55.41 other | oral | - | oral | REACH |
| NOAEL | >=0.05 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Well-tolerated ingredient with established food-grade safety; mild irritation possible at high concentrations due to acidity.
Regulatory Flags
Frequently Asked Questions
Is Calcium Acetate safe in cosmetics?
Well-tolerated ingredient with established food-grade safety; mild irritation possible at high concentrations due to acidity. The EU classifies Calcium Acetate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Calcium Acetate allowed in the EU?
Calcium Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Acetate do in cosmetics?
Calcium Acetate functions as: Masking, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 62-54-4.
What is the Margin of Safety for Calcium Acetate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Calcium Acetate?
The NOAEL (No Observed Adverse Effect Level) for Calcium Acetate is 1500 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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