Phenacetin

INCI: PHENACETIN

CAS Number
62-44-2 [^1_1]
Function
Stabilizing agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not FDA-banned for cosmetics specifically, but classified as IARC Group 2A probable carcinogen; FDA would consider adulterated if unsafe

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

IARC Group 2A carcinogen with EU CMR Carc. 1B classification; banned in EU cosmetics due to nephrotoxicity and methemoglobinemia risk.

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Concern Level: High

Regulatory Flags

prop65

Frequently Asked Questions

Is Phenacetin safe in cosmetics?

IARC Group 2A carcinogen with EU CMR Carc. 1B classification; banned in EU cosmetics due to nephrotoxicity and methemoglobinemia risk. The EU classifies Phenacetin as "prohibited". Safety rating: POOR.

Is Phenacetin allowed in the EU?

Phenacetin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Phenacetin do in cosmetics?

Phenacetin functions as: Stabilizing agent. It is classified as a cosmetic ingredient in our database. CAS number: 62-44-2 [^1_1].

What is the Margin of Safety for Phenacetin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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