Good Colorant NOAEL Data GHS Classified

Calcium Carbonate — Structured Cosmetic Ingre

INCI: CALCIUM CARBONATE

CAS Number
471-34-1
Function
Colorant, absorbent, bulking agent, opacifying agent, abrasive, oral care agent, pH adjuster
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 35%
🇺🇸 US Status permitted
US Notes No specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Calcium Carbonate — Structured Cosmetic Ingre. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3000 mg/kg bw/day oral mouse Reproductive COSMOS_DB
NOAEL 300 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1015 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 9989 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1349 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 385 mg/kg bw/day oral rat Developmental COSMOS_DB
dose_tested 1015 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL >1000 mg/kg bw/day oral - oral REACH
NOAEL >1000 mg/kg bw/day oral - oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Hazard Statements
No hazard classification according to GHS criteria
Short-term Exposure Effects
May cause mechanical irritation to the respiratory tract and eyes.
Long-term Exposure Effects
Health effects of the substance have been investigated but none have been found

Expert Verdict

Calcium Carbonate is generally considered safe for use as an absorbent, bulking agent, opacifying agent, abrasive, oral care agent, and pH adjuster.

⚠️
Concern Level: Low

Regulatory Flags

eu_children_restricted epa_safer_alternative fda_food_additive eu_cosing_listed

Frequently Asked Questions

Is Calcium Carbonate — Structured Cosmetic Ingre safe in cosmetics?

Calcium Carbonate is generally considered safe for use as an absorbent, bulking agent, opacifying agent, abrasive, oral care agent, and pH adjuster. The EU classifies Calcium Carbonate — Structured Cosmetic Ingre as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Calcium Carbonate — Structured Cosmetic Ingre allowed in the EU?

Calcium Carbonate — Structured Cosmetic Ingre EU regulatory status: permitted. Maximum allowed concentration: 35%. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Carbonate — Structured Cosmetic Ingre do in cosmetics?

Calcium Carbonate — Structured Cosmetic Ingre functions as: Colorant, absorbent, bulking agent, opacifying agent, abrasive, oral care agent, pH adjuster. It is classified as a Colorant in our database. CAS number: 471-34-1.

What is the Margin of Safety for Calcium Carbonate — Structured Cosmetic Ingre?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Calcium Carbonate — Structured Cosmetic Ingre?

The NOAEL (No Observed Adverse Effect Level) for Calcium Carbonate — Structured Cosmetic Ingre is 3000 mg/kg bw/day based on a Reproductive study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.

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