Moderate Cosmetic Ingredient

Calcium/Magnesium/Zinc Hydroxyapatite

INCI: CALCIUM/MAGNESIUM/ZINC HYDROXYAPATITE

CAS Number
Not individually assigned (base HA: 1306-06-5)
Function
Abrasive; Bulking agent; Oral care agent; Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Requires verification – No specific MoS data for this substituted variant; read-across from base HA with additional zinc exposure assessment needed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Zinc ion release should be accounted for in cumulative zinc exposure calculations. More limited specific safety data than base HA.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Calcium/Magnesium/Zinc Hydroxyapatite safe in cosmetics?

Zinc ion release should be accounted for in cumulative zinc exposure calculations. More limited specific safety data than base HA. The EU classifies Calcium/Magnesium/Zinc Hydroxyapatite as "restricted". Safety rating: MODERATE.

Is Calcium/Magnesium/Zinc Hydroxyapatite allowed in the EU?

Calcium/Magnesium/Zinc Hydroxyapatite EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium/Magnesium/Zinc Hydroxyapatite do in cosmetics?

Calcium/Magnesium/Zinc Hydroxyapatite functions as: Abrasive; Bulking agent; Oral care agent; Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (base HA: 1306-06-5).

What is the Margin of Safety for Calcium/Magnesium/Zinc Hydroxyapatite?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Calcium/Magnesium/Zinc Hydroxyapatite compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Pentapeptide-53
Moderate
Methylsilanol Hydroxyproline Aspartate
Moderate
Eugenia Cumini Root Extract
Moderate
Acetylneuraminic Acid
Excellent
Butyl Glycolate
Good
Browse all 30,000+ ingredients →
📱

Is Calcium/Magnesium/Zinc Hydroxyapatite in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Calcium/Magnesium/Zinc Hydroxyapatite in your formulation.

Ingredient Decoder MoS Calculator