Moderate Cosmetic Ingredient

Calcium/Strontium Hydroxyapatite

INCI: CALCIUM/STRONTIUM HYDROXYAPATITE

CAS Number
Not individually assigned (base HA: 1306-06-5)
Function
Abrasive; Bulking agent; Oral care agent; Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Requires verification. Strontium ion bioavailability and release kinetics must be characterized; no published MoS for this specific variant.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strontium accumulation in bone is a known concern; oral care use requires strontium release and bioavailability data. Limited ingredient-specific safety data available; read-across from base hydroxyapatite is necessary but insufficient for the strontium component.

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Concern Level: Moderate

Frequently Asked Questions

Is Calcium/Strontium Hydroxyapatite safe in cosmetics?

Strontium accumulation in bone is a known concern; oral care use requires strontium release and bioavailability data. Limited ingredient-specific safety data available; read-across from base hydroxyapatite is necessary but insufficient for the strontium component. The EU classifies Calcium/Strontium Hydroxyapatite as "restricted". Safety rating: MODERATE.

Is Calcium/Strontium Hydroxyapatite allowed in the EU?

Calcium/Strontium Hydroxyapatite EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium/Strontium Hydroxyapatite do in cosmetics?

Calcium/Strontium Hydroxyapatite functions as: Abrasive; Bulking agent; Oral care agent; Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (base HA: 1306-06-5).

What is the Margin of Safety for Calcium/Strontium Hydroxyapatite?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Calcium/Strontium Hydroxyapatite compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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