Is Caprylyl Butyrate safe in cosmetics?
Caprylyl Butyrate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Caprylyl Butyrate
Also known as: Butyric acid, octyl ester, EINECS 203-762-4, FEMA No. 2807, NSC 72032, Octyl butanoate (+7 more)
INCI: CAPRYLYL BUTYRATE
Caprylyl Butyrate (CAS 110-39-4) is a cosmetic cosmetic ingredient functioning as Fragrance, Emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 110-39-4 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Emollient
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
octyl butanoate
InChIKey
PWLNAUNEAKQYLH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted; CIR-assessed within alkyl esters group
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Caprylyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
155
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
OCTYL BUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Fragrance
Softener and conditioner
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Caprylyl Butyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Butyric acid, octyl ester
EINECS 203-762-4
FEMA No. 2807
NSC 72032
Octyl butanoate
n-Octyl butyrate
n-Octyl n-butyrate
UNII-5YEU4O369L
Butyric acid, octyl ester (8CI)
FEMA 2807
N-Octyl butanoate
Octyl butyrate
Chemical Function
Deodorizer
Softener and conditioner
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL4634201
Frequently Asked Questions
Is Caprylyl Butyrate allowed in the EU?
Caprylyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Caprylyl Butyrate do in cosmetics?
Caprylyl Butyrate functions as: Fragrance, Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 110-39-4.
Is Caprylyl Butyrate used outside cosmetics?
Caprylyl Butyrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Caprylyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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