Good Antioxidant NOAEL Data

Catalase Cosmetic Ingredient

INCI: CATALASE

CAS Number
9001-05-2
Function
Antioxidant enzyme that catalyzes the breakdown of hydrogen peroxide in cosmetic formulations
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Catalase Cosmetic Ingredient. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

Catalase is a protein enzyme functioning as an antioxidant, with no specific regulatory restrictions in EU or US markets.

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Concern Level: Low

Regulatory Flags

Allergen eu_banned_cosmetics epa_safer_alternative eu_cosing_listed

Frequently Asked Questions

Is Catalase Cosmetic Ingredient safe in cosmetics?

Catalase is a protein enzyme functioning as an antioxidant, with no specific regulatory restrictions in EU or US markets. The EU classifies Catalase Cosmetic Ingredient as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Catalase Cosmetic Ingredient allowed in the EU?

Catalase Cosmetic Ingredient EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Catalase Cosmetic Ingredient do in cosmetics?

Catalase Cosmetic Ingredient functions as: Antioxidant enzyme that catalyzes the breakdown of hydrogen peroxide in cosmetic formulations. It is classified as a Antioxidant in our database. CAS number: 9001-05-2.

What is the Margin of Safety for Catalase Cosmetic Ingredient?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Catalase Cosmetic Ingredient?

The NOAEL (No Observed Adverse Effect Level) for Catalase Cosmetic Ingredient is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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