Cayenne Pepper Extract

INCI: CAPSICUM ANNUUM FRUIT EXTRACT

CAS Number
84625-29-6
Function
Warming agent, counterirritant; capsaicin TRPV1 agonist
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: capsaicin OTC analgesic monograph at 0.025-0.25%.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe at low concentrations (0.01-0.1% capsaicin) with careful formulation; avoid contact with eyes and mucous membranes due to TRPV1-mediated irritation.

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Concern Level: Moderate

Regulatory Flags

eu_children_restricted ifra_fragrance

Frequently Asked Questions

Is Cayenne Pepper Extract safe in cosmetics?

Safe at low concentrations (0.01-0.1% capsaicin) with careful formulation; avoid contact with eyes and mucous membranes due to TRPV1-mediated irritation. The EU classifies Cayenne Pepper Extract as "permitted". Safety rating: MODERATE.

Is Cayenne Pepper Extract allowed in the EU?

Cayenne Pepper Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cayenne Pepper Extract do in cosmetics?

Cayenne Pepper Extract functions as: Warming agent, counterirritant; capsaicin TRPV1 agonist. It is classified as a Cosmetic Ingredient in our database. CAS number: 84625-29-6.

What is the Margin of Safety for Cayenne Pepper Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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