Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Docosane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Petrochemical origin requires verification of PAH (polycyclic aromatic hydrocarbons) content per EP/USP mineral hydrocarbon purity standards; ensure cosmetic-grade specification.
Regulatory Flags
Frequently Asked Questions
Is Docosane safe in cosmetics?
Petrochemical origin requires verification of PAH (polycyclic aromatic hydrocarbons) content per EP/USP mineral hydrocarbon purity standards; ensure cosmetic-grade specification. The EU classifies Docosane as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.
Is Docosane allowed in the EU?
Docosane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Docosane do in cosmetics?
Docosane functions as: Skin conditioning agent – emollient; viscosity increasing agent. It is classified as a cosmetic ingredient in our database. CAS number: 629-97-0.
What is the Margin of Safety for Docosane?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Docosane?
The NOAEL (No Observed Adverse Effect Level) for Docosane is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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