Cinoxate

INCI: CINOXATE

CAS Number
104-28-9
Function
UV Filter (UVB absorber, peak at 289 nm)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA-approved OTC sunscreen active at โ‰ค3% concentration; however, FDA has not determined GRAS status due to insufficient safety data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cinoxate undergoes photodegradation under UV exposure forming unknown degradation products, provides minimal SPF benefit (~1-2 units at max concentration), and has not been approved in the EU, Japan, or Australia despite grandfathered FDA approval from 1978 without modern safety review.

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Concern Level: High

Frequently Asked Questions

Is Cinoxate safe in cosmetics?

Cinoxate undergoes photodegradation under UV exposure forming unknown degradation products, provides minimal SPF benefit (~1-2 units at max concentration), and has not been approved in the EU, Japan, or Australia despite grandfathered FDA approval from 1978 without modern safety review. The EU classifies Cinoxate as "prohibited". Safety rating: MODERATE.

Is Cinoxate allowed in the EU?

Cinoxate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cinoxate do in cosmetics?

Cinoxate functions as: UV Filter (UVB absorber, peak at 289 nm). It is classified as a cosmetic ingredient in our database. CAS number: 104-28-9.

What is the Margin of Safety for Cinoxate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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