Excellent Cosmetic Ingredient NOAEL Data

cis-Jasmone

INCI: CIS-JASMONE

CAS Number
488-10-8
Function
Fragrance (jasmine floral note)
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes RIFM assessed โ€” safe as described; IFRA 51st Amendment compliant at up to 100% in non-skin contact applications

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for cis-Jasmone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1500 ppm oral rat oral REACH

Expert Verdict

Not PBT per IFRA Environmental Standards; PEC/PNEC <1; not phototoxic or photoallergenic; IFRA generally unrestricted for non-skin contact applications.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is cis-Jasmone safe in cosmetics?

Not PBT per IFRA Environmental Standards; PEC/PNEC <1; not phototoxic or photoallergenic; IFRA generally unrestricted for non-skin contact applications. The EU classifies cis-Jasmone as "restricted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.

Is cis-Jasmone allowed in the EU?

cis-Jasmone EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does cis-Jasmone do in cosmetics?

cis-Jasmone functions as: Fragrance (jasmine floral note). It is classified as a cosmetic ingredient in our database. CAS number: 488-10-8.

What is the Margin of Safety for cis-Jasmone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for cis-Jasmone?

The NOAEL (No Observed Adverse Effect Level) for cis-Jasmone is 1500 ppm based on a oral study via oral route in rat. Source: REACH.

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