Citrate Buffer

INCI: CITRIC ACID + SODIUM CITRATE

CAS Number
Typically composed of Citric Acid (77-92-9) + Sodium Citrate (68-04-2) or Potassium Citrate (866-84-2)
Function
pH buffering agent, chelating agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed โ€” safe as used in present practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

At very high concentrations, citric acid is an AHA that may cause irritation; keep buffered pH within product specification; no significant safety concerns at normal buffering levels

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Concern Level: Low

Frequently Asked Questions

Is Citrate Buffer safe in cosmetics?

At very high concentrations, citric acid is an AHA that may cause irritation; keep buffered pH within product specification; no significant safety concerns at normal buffering levels The EU classifies Citrate Buffer as "permitted". Safety rating: EXCELLENT.

Is Citrate Buffer allowed in the EU?

Citrate Buffer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrate Buffer do in cosmetics?

Citrate Buffer functions as: pH buffering agent, chelating agent. It is classified as a cosmetic ingredient in our database. CAS number: Typically composed of Citric Acid (77-92-9) + Sodium Citrate (68-04-2) or Potassium Citrate (866-84-2).

What is the Margin of Safety for Citrate Buffer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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