Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Citronellal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 345 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 745 mg/kg bw/day | oral | mouse | oral | REACH |
| LOAEL | 210 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 60 mg/kg bw/day | oral | mouse | oral | REACH |
| LOAEL | 345 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 745 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 210 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 60 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
EU allergen under Regulation 2023/1545 with label compliance deadline July 31, 2026; oxidation products increase sensitization potential; IFRA category limits must be observed; cross-reactivity with citral and hydroxycitronellal
Regulatory Flags
Frequently Asked Questions
Is Citronellal safe in cosmetics?
EU allergen under Regulation 2023/1545 with label compliance deadline July 31, 2026; oxidation products increase sensitization potential; IFRA category limits must be observed; cross-reactivity with citral and hydroxycitronellal The EU classifies Citronellal as "restricted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.
Is Citronellal allowed in the EU?
Citronellal EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellal do in cosmetics?
Citronellal functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 106-23-0.
What is the Margin of Safety for Citronellal?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Citronellal?
The NOAEL (No Observed Adverse Effect Level) for Citronellal is 345 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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