Is Citronellal Dimethyl Acetal safe in cosmetics?
Citronellal Dimethyl Acetal has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted.
Good
Cosmetic Ingredient
Citronellal Dimethyl Acetal
Also known as: 2,6-Octadiene, 1,1-dimethoxy-3,7-dimethyl-, Citral dimethyl acetal, 4-01-00-03570, BRN 1706336, 1,1-Dimethoxy-3,7-dimethyl-2,6-octadiene (+5 more)
INCI: CITRONELLAL DIMETHYL ACETAL
Citronellal Dimethyl Acetal (CAS 7549-37-3) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (floral/green note modifier). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 7549-37-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Citronellal Dimethyl Acetal is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Fragrance ingredient (floral/green note modifier)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1,1-dimethoxy-3,7-dimethylocta-2,6-diene
InChIKey
ZSKAJFSSXURRGL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
RIFM safety assessment available for structurally analogous hydroxycitronellal dimethyl acetal (CAS 141-92-4) — found safe at current use levels
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Citronellal Dimethyl Acetal.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
944
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
3,7-DIMETHYL-2,6-OCTADIENYL DIMETHYL ACETAL | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/107 | FAS 48-JECFA 57/369
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CITRAL DIMETHYL ACETAL | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/107 | FAS 48-JECFA 57/369
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Citronellal Dimethyl Acetal.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
2,6-Octadiene, 1,1-dimethoxy-3,7-dimethyl-
Citral dimethyl acetal
4-01-00-03570
BRN 1706336
1,1-Dimethoxy-3,7-dimethyl-2,6-octadiene
3,7-Dimethyl-2,6-octadienal dimethyl acetal
EINECS 231-434-0
FEMA No. 2305
2,6-Octadienal, 3,7-dimethyl-, dimethyl acetal
UNII-6ZOD5NW633
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CITRAL DIMETHYL ACETAL
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Citronellal Dimethyl Acetal allowed in the EU?
Citronellal Dimethyl Acetal EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellal Dimethyl Acetal do in cosmetics?
Citronellal Dimethyl Acetal functions as: Fragrance ingredient (floral/green note modifier). It is classified as a cosmetic ingredient in our database. CAS number: 7549-37-3.
Is Citronellal Dimethyl Acetal used outside cosmetics?
Citronellal Dimethyl Acetal also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Citronellal Dimethyl Acetal have different safety status in cosmetics vs industrial chemicals?
Citronellal Dimethyl Acetal is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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