Is p-Anisyl Propionate safe in cosmetics?
p-Anisyl Propionate has a safety rating of "EXCELLENT" in our database. EU status: restricted. US status: permitted.
Excellent
Cosmetic Ingredient
p-Anisyl Propionate
Also known as: Benzyl alcohol, P-methoxy-, propionate, EINECS 231-433-5, FEMA No. 2102, 4-Methoxybenzenemethanol propanoate, 4-Methoxybenzenemethyl propanoate (+3 more)
INCI: ANISYL PROPIONATE
p-Anisyl Propionate (CAS 7549-33-9) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: restricted, max 0.13%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 7549-33-9 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(4-methoxyphenyl)methyl propanoate
InChIKey
YWIJRJQYADFRTL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.13%
US US Status
permitted
US Notes
FDA not specifically restricted; general cosmetic use permitted under FDCA §601
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for p-Anisyl Propionate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
874
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
p-METHOXYBENZYL PROPIONATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ANISYL PROPIONATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for p-Anisyl Propionate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Benzyl alcohol, P-methoxy-, propionate
EINECS 231-433-5
FEMA No. 2102
4-Methoxybenzenemethanol propanoate
4-Methoxybenzenemethyl propanoate
NSC 46113
Propionic acid, p-methoxybenzyl ester
UNII-IBJ5CR95MK
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3188412
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ANISYL PROPIONATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is p-Anisyl Propionate allowed in the EU?
p-Anisyl Propionate EU regulatory status: restricted. Maximum allowed concentration: 0.13%. This is based on EU Regulation 1223/2009 and its amendments.
What does p-Anisyl Propionate do in cosmetics?
p-Anisyl Propionate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 7549-33-9.
Is p-Anisyl Propionate used outside cosmetics?
p-Anisyl Propionate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check p-Anisyl Propionate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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