Excellent Cosmetic Ingredient NOAEL Data

Coco-Caprylate/Caprate

Also known as: Captex 170EP

INCI: COCO-CAPRYLATE/CAPRATE

Coco-Caprylate/Caprate (CAS 95912-86-0) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning, hair conditioning. NOAEL 800 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 95912-86-0 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, skin conditioning, hair conditioning
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C42H84O4
MW
653.1 g/mol
EC Number
306-082-7
PubChem CID
133082067
IUPAC Name
dodecyl decanoate;dodecyl octanoate
InChIKey
XJFGDLJQUJQUEI-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not restricted by FDA. CIR reviewed as part of 239 alkyl esters group — concluded safe as used when formulated to be non-irritating.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Coco-Caprylate/Caprate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Coco-Caprylate/Caprate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Coco-Caprylate/Caprate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "c…
comedogenicity_detail
{"comedogenicity_rating": "1", "irritancy_rating": "0", "skin_type_suitability": "all,oily,combination,normal,acne-prone", "acne_safe": "yes", "source": "Light ester"}
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "10", "estimated_cost_per_kg_usd_high": "18", "natural_premium_markup_pct": "15", "organic_certified_premium_pct": "28", "supply_chain_volatility": "low", "primary_source_region": "Europe/Malaysia", "synthetic_vs_natural_cost_ratio": "1.8", "bulk_discount_threshold_kg": "300", "seasonal_price_variation": "low", "commodity_or_specialty": "…
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "palm_…
lipid
{"cas_number": "160391-53-7", "lipid_class": "ester", "botanical_source": "synthetic/derived", "plant_part": "derived", "extraction_method": "refined", "fatty_acid_profile_main_pct": "light coconut ester", "omega_classification": "saturated", "comedogenicity_rating_0_5": "1", "absorption_rate": "fast", "skin_feel": "dry", "spreadability": "excellent", "emollient_grade": "A_excellent", "primary_app…
ph_stability
{"optimal_ph_min": "3.0", "optimal_ph_max": "10.0", "stable_ph_min": "3.0", "stable_ph_max": "11.0", "ph_dependent_function": "Natural emollient ester", "formulation_note": "Fast-spreading", "source": "Formulation literature"}
sensory
{"silky": "light", "smooth, glides easily": "light, silky", "dry-touch, non-greasy": "dry-touch, smooth", "instant": "fast", "low": "low", "w/o": "o/w", "very-high": "excellent", "no": "no", "yes": "no", "1.40": "1.45", "transparent": "transparent", "colorless": "colorless", "excellent": "excellent", "light": "light", "synthetic": "botanical"}
silicone
{"cas_number": "Not silicone", "silicone_class": "other", "molecular_weight_Da": "310.0", "viscosity_cSt": "12", "volatility": "non_volatile", "evaporation_rate_relative_to_D5": "0.12", "refractive_index": "1.44", "specific_gravity": "0.855", "flash_point_C": "135.0", "surface_tension_mN_m": "26.8", "spreading_coefficient": "3.2", "film_forming_ability": "good", "skin_feel": "silky", "slip_and_gli…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance Plasticizer
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Coco-Caprylate/Caprate.

Regulatory Flags

ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Coco-Caprylate/Caprate by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Captex 170EP

Chemical Function

Plasticizer Fragrance

Regulatory Lists

Europe; plastic_additive IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Coco-Caprylate/Caprate safe in cosmetics?

Coco-Caprylate/Caprate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Coco-Caprylate/Caprate allowed in the EU?

Coco-Caprylate/Caprate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coco-Caprylate/Caprate do in cosmetics?

Coco-Caprylate/Caprate functions as: Emollient, skin conditioning, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 95912-86-0.

What is the NOAEL for Coco-Caprylate/Caprate?

The NOAEL (No Observed Adverse Effect Level) for Coco-Caprylate/Caprate is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Coco-Caprylate/Caprate used outside cosmetics?

Coco-Caprylate/Caprate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Is Coco-Caprylate/Caprate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Coco-Caprylate/Caprate in your formulation.