Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Coco-Caprylate/Caprate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 800 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 800 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Alkyl ester emollient with low absorption and no sensitization risk; formulate to be non-irritating and avoid combining with ingredients where penetration enhancement poses safety concerns.
Regulatory Flags
Frequently Asked Questions
Is Coco-Caprylate/Caprate safe in cosmetics?
Alkyl ester emollient with low absorption and no sensitization risk; formulate to be non-irritating and avoid combining with ingredients where penetration enhancement poses safety concerns. The EU classifies Coco-Caprylate/Caprate as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Coco-Caprylate/Caprate allowed in the EU?
Coco-Caprylate/Caprate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coco-Caprylate/Caprate do in cosmetics?
Coco-Caprylate/Caprate functions as: Emollient, skin conditioning, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 95912-86-0.
What is the Margin of Safety for Coco-Caprylate/Caprate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Coco-Caprylate/Caprate?
The NOAEL (No Observed Adverse Effect Level) for Coco-Caprylate/Caprate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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