Excellent Cosmetic Ingredient NOAEL Data

Cocos Nucifera Seed Butter

INCI: COCOS NUCIFERA SEED BUTTER

CAS Number
8001-31-8
Function
Skin-conditioning agent – emollient; viscosity increasing agent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA restrictions; CIR Panel concluded safe in 2017 as part of the plant-derived fatty acid oils group (244 ingredients)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Cocos Nucifera Seed Butter. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4850 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 20000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1817 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1777 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1772 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1780 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 4000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7000 mg/kg bw/day oral gerbil Short Term Toxicity COSMOS_DB
NOAEL 22500 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Expert Verdict

Persons with confirmed coconut allergy (rare, IgE-mediated) should avoid; comedogenic potential in facial leave-on products.

⚠️
Concern Level: Low

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Cocos Nucifera Seed Butter safe in cosmetics?

Persons with confirmed coconut allergy (rare, IgE-mediated) should avoid; comedogenic potential in facial leave-on products. The EU classifies Cocos Nucifera Seed Butter as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Cocos Nucifera Seed Butter allowed in the EU?

Cocos Nucifera Seed Butter EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocos Nucifera Seed Butter do in cosmetics?

Cocos Nucifera Seed Butter functions as: Skin-conditioning agent – emollient; viscosity increasing agent. It is classified as a cosmetic ingredient in our database. CAS number: 8001-31-8.

What is the Margin of Safety for Cocos Nucifera Seed Butter?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cocos Nucifera Seed Butter?

The NOAEL (No Observed Adverse Effect Level) for Cocos Nucifera Seed Butter is 4850 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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