Regulatory Status
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Safety Data
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Expert Verdict
Major data gaps across all required safety endpoints; no dermal NOAEL, no SCCS or CIR opinion, no MoS calculable; extraordinarily high transdermal penetration reported (72%); pharmacologically active as adenylyl cyclase activator with H312 GHS classification and absence of published HRIPT or LLNA data.
Regulatory Flags
Frequently Asked Questions
Is Coleus Barbatus Root Extract safe in cosmetics?
Major data gaps across all required safety endpoints; no dermal NOAEL, no SCCS or CIR opinion, no MoS calculable; extraordinarily high transdermal penetration reported (72%); pharmacologically active as adenylyl cyclase activator with H312 GHS classification and absence of published HRIPT or LLNA data. The EU classifies Coleus Barbatus Root Extract as "permitted". Safety rating: POOR.
Is Coleus Barbatus Root Extract allowed in the EU?
Coleus Barbatus Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coleus Barbatus Root Extract do in cosmetics?
Coleus Barbatus Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 223748-52-5.
What is the Margin of Safety for Coleus Barbatus Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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