Is Cysteamine HCl safe in cosmetics?
Cysteamine HCl has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
GOOD
Cosmetic Ingredient
Cysteamine HCl
Also known as: Ethanethiol, 2-amino-, hydrochloride, Ethanethiol, 2-amino-, hydrochloride (1:1), Mercaptamine hydrochloride, 1-Aminoethane-2-thiol hydrochloride, Bekaptan (+8 more)
INCI: CYSTEAMINE HCL
Cysteamine HCl (CAS 156-57-0) is a cosmetic cosmetic ingredient functioning as Skin Brightening. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Skin Brightening
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
EC Number
205-858-1
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Status permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cysteamine HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | restricted | 5 | Hair waving/straightening products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Hair waving or straightening
Reducing agent
Editorial summary
Preliminary editorial summary for Cysteamine HCl — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
EU Restricted
Known Synonyms
Ethanethiol, 2-amino-, hydrochloride
Ethanethiol, 2-amino-, hydrochloride (1:1)
Mercaptamine hydrochloride
1-Aminoethane-2-thiol hydrochloride
Bekaptan
EINECS 205-858-1
Ethylamine, 2-mercapto-, hydrochloride
Mercaptoethylamine hydrochloride
NSC 21116
eta-Mercaptoethylamine hydrochloride
beta-Mercaptoaethylamin chlorhydrat
Cysteaminhydrochlorid
UNII-IF1B771SVB
Chemical Function
Antioxidant
Reducing agent
Hair waving or straightening
Regulatory Lists
pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CYSTEAMINE HYDROCHLORIDE
ChEMBL ID
CHEMBL1256137
Max Phase
4
Adverse Event Associations
22
Frequently Asked Questions
Is Cysteamine HCl allowed in the EU?
Cysteamine HCl EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cysteamine HCl do in cosmetics?
Cysteamine HCl functions as: Skin Brightening. It is classified as a cosmetic ingredient in our database. CAS number: 156-57-0.
Is Cysteamine HCl used outside cosmetics?
Cysteamine HCl also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cysteamine HCl compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Arginine
EXCELLENT
Same category
Amino acid / pH Adjuster
D-Panthenol
EXCELLENT
Same category
Hair and skin conditioning, humectant...
Dicaprylyl Ether
EXCELLENT
Same category
Emollient
Emulsifying Wax
EXCELLENT
Same category
O/W emulsifier; stabilizes oil-in-wat...
Ethyl Butyrate
EXCELLENT
Same category
Perfuming, Masking
Fructose
EXCELLENT
Same category
Humectant, Skin Conditioning, Flavori...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
GOOD
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
GOOD
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
GOOD
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
GOOD
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
GOOD
Similar safety
Antioxidant
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
GOOD
Similar safety
Humectant, Skin Conditioning - Humect...
Cysteamine
MODERATE
Chemical family
Multi-mechanism depigmenting aminothi...
P-PHENETIDINE
MODERATE
Chemical family
Hair Dyeing
CYSTEINE HCL
GOOD
Browse nearby
Antioxidant, Hair Conditioning, Hair ...
Is Cysteamine HCl in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cysteamine HCl in your formulation.