Is D&C Red No. 6 safe in cosmetics?
D&C Red No. 6 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Colorant
D&C Red No. 6
INCI: D&C RED NO. 6
D&C Red No. 6 (CAS 5858-81-1) is a cosmetic colorant functioning as colorant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 5858-81-1 →
Auto-generated CPSR Part A draft with source citations
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Subject to mandatory FDA batch certification per 21 CFR 74.2306. Combined D&C Red No. 6 + No. 7 limit of 5 mg/daily dose applies to drug products. Prohibited in eye-area cosmetics.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for D&C Red No. 6.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for D&C Red No. 6.
Regulatory Flags
batch-certification-required
not-for-eye-area
azo-dye
sccs-reviewed
color-additive
eu_cosing_listed
Frequently Asked Questions
Is D&C Red No. 6 allowed in the EU?
D&C Red No. 6 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does D&C Red No. 6 do in cosmetics?
D&C Red No. 6 functions as: colorant. It is classified as a Colorant in our database. CAS number: 5858-81-1.
Compliance Tools
Check D&C Red No. 6 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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