Good Colorant

D&C Red No. 6

INCI: D&C RED NO. 6

CAS Number
5858-81-1
Function
colorant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Subject to mandatory FDA batch certification per 21 CFR 74.2306. Combined D&C Red No. 6 + No. 7 limit of 5 mg/daily dose applies to drug products. Prohibited in eye-area cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

D&C Red No. 6 is an FDA-approved batch-certified color additive permitted in general cosmetics and lip products but prohibited in eye-area formulations; EU approved under Annex IV of Regulation EC 1223/2009.

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Concern Level: Low

Regulatory Flags

batch-certification-required not-for-eye-area azo-dye sccs-reviewed color-additive eu_cosing_listed

Frequently Asked Questions

Is D&C Red No. 6 safe in cosmetics?

D&C Red No. 6 is an FDA-approved batch-certified color additive permitted in general cosmetics and lip products but prohibited in eye-area formulations; EU approved under Annex IV of Regulation EC 1223/2009. The EU classifies D&C Red No. 6 as "permitted". Safety rating: GOOD.

Is D&C Red No. 6 allowed in the EU?

D&C Red No. 6 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does D&C Red No. 6 do in cosmetics?

D&C Red No. 6 functions as: colorant. It is classified as a Colorant in our database. CAS number: 5858-81-1.

What is the Margin of Safety for D&C Red No. 6?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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