Diazolidinyl Urea
INCI: DIAZOLIDINYL UREA
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Urea along with the comments that were received. The Panel concluded that this ingredient could be safely used in cosmetic products at the minimum effective concentration. The effective use and safety test data indicate that the potential of this ingredient to produce adverse reactions should be min
Sensitization Profile
Contact sensitization data for Diazolidinyl Urea based on clinical patch test studies and IFRA standards.
Source: ESSCA 2019/20; IVDK; FDA
Dermal Penetration Profile
Skin absorption and penetration characteristics of Diazolidinyl Urea, relevant to systemic exposure and MoS calculations.
Source: CIR
Expert Verdict
Formaldehyde releaser restricted under EU Annex V (maximum 0.5% leave-on products). Washington State ban effective January 1, 2027. High contact sensitization potential (2-4% positive patch test rate) due to formaldehyde release. IARC Group 1 carcinogen concern. No longer justifiable where alternatives available; federal US restriction expected to follow state-level bans.
Regulatory Flags
Frequently Asked Questions
Is Diazolidinyl Urea safe in cosmetics?
Formaldehyde releaser restricted under EU Annex V (maximum 0.5% leave-on products). Washington State ban effective January 1, 2027. High contact sensitization potential (2-4% positive patch test rate) due to formaldehyde release. IARC Group 1 carcinogen concern. No longer justifiable where alternatives available; federal US restriction expected to follow state-level bans. The EU classifies Diazolidinyl Urea as "restricted". Safety rating: MODERATE. This ingredient has been reviewed by cir.
Is Diazolidinyl Urea allowed in the EU?
Diazolidinyl Urea EU regulatory status: restricted. Maximum allowed concentration: 0.5% (face leave-on); 0.6% (rinse-off). This is based on EU Regulation 1223/2009 and its amendments.
What does Diazolidinyl Urea do in cosmetics?
Diazolidinyl Urea functions as: Preservative. It is classified as a Preservative in our database. CAS number: 78491-02-8.
What is the Margin of Safety for Diazolidinyl Urea?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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