Poor Cosmetic Ingredient

Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer

INCI: DIETHYLENE GLYCOLAMINE/EPICHLOROHYDRIN/PIPERAZINE COPOLYMER

CAS Number
Not individually assigned (cationic polymer)
Function
Antistatic, hair conditioning (cationic polyelectrolyte)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted as finished polymer — no CFR ban on polymer itself

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical: Epichlorohydrin is classified CMR (Carcinogen 1B, Mutagen 2) and is EU Annex II–prohibited as a substance; residual levels in the polymer must be tightly controlled and documented. Piperazine is a respiratory and skin sensitiser. Canada Hotlist lists epichlorohydrin as prohibited. Certificate of Analysis specifying residual monomers required for every batch.

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Concern Level: High

Frequently Asked Questions

Is Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer safe in cosmetics?

Critical: Epichlorohydrin is classified CMR (Carcinogen 1B, Mutagen 2) and is EU Annex II–prohibited as a substance; residual levels in the polymer must be tightly controlled and documented. Piperazine is a respiratory and skin sensitiser. Canada Hotlist lists epichlorohydrin as prohibited. Certificate of Analysis specifying residual monomers required for every batch. The EU classifies Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer as "prohibited". Safety rating: POOR.

Is Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer allowed in the EU?

Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer do in cosmetics?

Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer functions as: Antistatic, hair conditioning (cationic polyelectrolyte). It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (cationic polymer).

What is the Margin of Safety for Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Diethylene Glycolamine/Epichlorohydrin/Piperazine Copolymer compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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