Diisoamyl Malate

INCI: DIISOAMYL MALATE

CAS Number
1587-19-5
Function
Skin conditioning agent – emollient
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR Expert Panel concluded safe in present practices of use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant safety concerns; minor maleic acid impurity from malic acid feedstock noted by CIR but at levels below toxicological concern.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Diisoamyl Malate safe in cosmetics?

No significant safety concerns; minor maleic acid impurity from malic acid feedstock noted by CIR but at levels below toxicological concern. The EU classifies Diisoamyl Malate as "permitted". Safety rating: EXCELLENT.

Is Diisoamyl Malate allowed in the EU?

Diisoamyl Malate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diisoamyl Malate do in cosmetics?

Diisoamyl Malate functions as: Skin conditioning agent – emollient. It is classified as a cosmetic ingredient in our database. CAS number: 1587-19-5.

What is the Margin of Safety for Diisoamyl Malate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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