Is Dimethyl Glutarate safe in cosmetics?
Dimethyl Glutarate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Dimethyl Glutarate
Also known as: Pentanedioic acid, dimethyl ester, DBE 5, NSC 58578, EINECS 214-277-2, UNII-1I9VFA346P (+1 more)
INCI: DIMETHYL GLUTARATE
Dimethyl Glutarate (CAS 1119-40-0) is a cosmetic cosmetic ingredient functioning as Solvent (dibasic ester). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1119-40-0 →
Auto-generated CPSR Part A draft with source citations
Function
Solvent (dibasic ester)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
dimethyl pentanedioate
InChIKey
XTDYIOOONNVFMA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR reviewed as part of dibasic ester group
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dimethyl Glutarate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter
Anti-static agent
Binder
Fragrance
Plasticizer
Softener and conditioner
Solubility enhancer
Solvent
Surface modifier
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Dimethyl Glutarate.
Regulatory Flags
epa_safer_alternative
ifra_fragrance
Known Synonyms
Pentanedioic acid, dimethyl ester
DBE 5
NSC 58578
EINECS 214-277-2
UNII-1I9VFA346P
1,5-Dimethyl pentanedioate
Chemical Function
Solvent
Softener and conditioner
Anti-static agent
Binder
Plasticizer
Surface modifier
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
SCIL (9/2019)
artificial_sweat; detected; emissions; Europe; Other direct contact consumer goods
artificial_saliva; detected; emissions; Europe; Other direct contact consumer goods
IFRA Transparency
inert_ingredient; non_food_use; Pesticides
artificial_saliva; detected; emissions; Europe; Toys and children's products
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1609626
Frequently Asked Questions
Is Dimethyl Glutarate allowed in the EU?
Dimethyl Glutarate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethyl Glutarate do in cosmetics?
Dimethyl Glutarate functions as: Solvent (dibasic ester). It is classified as a cosmetic ingredient in our database. CAS number: 1119-40-0.
Is Dimethyl Glutarate used outside cosmetics?
Dimethyl Glutarate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dimethyl Glutarate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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