Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Dimethyl Glutarate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 1000 mg/kg bw/day | dermal | rat | dermal | REACH |
Expert Verdict
Solvent with good safety profile; may cause irritation at high concentrations via inhalation, ingestion, or skin absorption; hydrolysis can produce trace methanol.
Regulatory Flags
Frequently Asked Questions
Is Dimethyl Glutarate safe in cosmetics?
Solvent with good safety profile; may cause irritation at high concentrations via inhalation, ingestion, or skin absorption; hydrolysis can produce trace methanol. The EU classifies Dimethyl Glutarate as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Dimethyl Glutarate allowed in the EU?
Dimethyl Glutarate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethyl Glutarate do in cosmetics?
Dimethyl Glutarate functions as: Solvent (dibasic ester). It is classified as a cosmetic ingredient in our database. CAS number: 1119-40-0.
What is the Margin of Safety for Dimethyl Glutarate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethyl Glutarate?
The NOAEL (No Observed Adverse Effect Level) for Dimethyl Glutarate is 1000 mg/kg bw/day based on a dermal study via dermal route in rat. Source: REACH.
Compliance Tools
Check Dimethyl Glutarate compliance across multiple jurisdictions:
Related Ingredients
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