Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
9 study endpoints found for Dimethyl Phthalate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1009 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=2700 mg/kg bw/day | dermal | code:3543 | dermal | REACH |
| NOAEL | 770 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1200 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 770 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 200 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
DMP carries a generous margin of safety of 13,500 per SCCP 2007 and is not restricted under EU Regulation 1223/2009 or by the FDA. However, its primary occurrence in cosmetics is as an unintentional contaminant from plastic packaging, and the broader industry trend toward phthalate-free formulations makes proactive elimination the preferred compliance position.
Regulatory Flags
Frequently Asked Questions
Is Dimethyl Phthalate safe in cosmetics?
DMP carries a generous margin of safety of 13,500 per SCCP 2007 and is not restricted under EU Regulation 1223/2009 or by the FDA. However, its primary occurrence in cosmetics is as an unintentional contaminant from plastic packaging, and the broader industry trend toward phthalate-free formulations makes proactive elimination the preferred compliance position. The EU classifies Dimethyl Phthalate as "permitted". Safety rating: MODERATE. 9 toxicological study endpoint(s) are available in our database.
Is Dimethyl Phthalate allowed in the EU?
Dimethyl Phthalate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethyl Phthalate do in cosmetics?
Dimethyl Phthalate functions as: Solvent, Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 131-11-3.
What is the Margin of Safety for Dimethyl Phthalate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethyl Phthalate?
The NOAEL (No Observed Adverse Effect Level) for Dimethyl Phthalate is >=1009 mg/kg bw/day based on a oral study via oral route in rat. A total of 9 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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