Is DIMETHYLAMINO METHYLPROPANOL safe in cosmetics?
DIMETHYLAMINO METHYLPROPANOL has a safety rating of "GOOD" in our database. EU status: permitted. 1 toxicological study endpoint(s) are available in our database.
DIMETHYLAMINO METHYLPROPANOL
Also known as: 1-Propanol, 2-(dimethylamino)-2-methyl-, BRN 1732837, 2-(Dimethylamino)-2-methylpropanol, 2-Dimethylamino-2-methyl-1-propanol, EINECS 230-279-6 (+2 more)
DIMETHYLAMINO METHYLPROPANOL (CAS 7005-47-2) is a cosmetic cosmetic ingredient functioning as Anticorrosive. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7005-47-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
DIMETHYLAMINO METHYLPROPANOL is classified GHS Danger (H226, H302, H314, H315, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Anticorrosive
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-(dimethylamino)-2-methylpropan-1-ol
InChIKey
XRIBIDPMFSLGFS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
1 study endpoint found for DIMETHYLAMINO METHYLPROPANOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =300 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for DIMETHYLAMINO METHYLPROPANOL across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Corrosion inhibitor
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for DIMETHYLAMINO METHYLPROPANOL.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to DIMETHYLAMINO METHYLPROPANOL by CAS number or substance name.
Studies
1
Lowest NOAEL
300 mg/kg bw/day
Highest NOAEL
300 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
1-Propanol, 2-(dimethylamino)-2-methyl-
BRN 1732837
2-(Dimethylamino)-2-methylpropanol
2-Dimethylamino-2-methyl-1-propanol
EINECS 230-279-6
NSC 17706
UNII-6ZWG40UQ9E
Chemical Function
Corrosion inhibitor
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182117
Frequently Asked Questions
Is DIMETHYLAMINO METHYLPROPANOL allowed in the EU?
DIMETHYLAMINO METHYLPROPANOL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does DIMETHYLAMINO METHYLPROPANOL do in cosmetics?
DIMETHYLAMINO METHYLPROPANOL functions as: Anticorrosive. It is classified as a cosmetic ingredient in our database. CAS number: 7005-47-2.
What is the NOAEL for DIMETHYLAMINO METHYLPROPANOL?
The NOAEL (No Observed Adverse Effect Level) for DIMETHYLAMINO METHYLPROPANOL is =300 mg/kg bw/day based on a chronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is DIMETHYLAMINO METHYLPROPANOL used outside cosmetics?
DIMETHYLAMINO METHYLPROPANOL also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does DIMETHYLAMINO METHYLPROPANOL have different safety status in cosmetics vs industrial chemicals?
DIMETHYLAMINO METHYLPROPANOL is classified GHS Danger (H226, H302, H314, H315, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check DIMETHYLAMINO METHYLPROPANOL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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