Regulatory Status
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Safety Data
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Expert Verdict
Strong reducing agent with GHS classification Acute Tox. 4 (H302), Skin Irrit. 2 (H315), Eye Irrit. 2 (H319) that disrupts disulfide bonds in proteins and attacks keratin; not intended for cosmetic application and would require full de novo toxicological package if cosmetic use were proposed
Frequently Asked Questions
Is Dithiothreitol (DTT) safe in cosmetics?
Strong reducing agent with GHS classification Acute Tox. 4 (H302), Skin Irrit. 2 (H315), Eye Irrit. 2 (H319) that disrupts disulfide bonds in proteins and attacks keratin; not intended for cosmetic application and would require full de novo toxicological package if cosmetic use were proposed The EU classifies Dithiothreitol (DTT) as "prohibited". Safety rating: POOR.
Is Dithiothreitol (DTT) allowed in the EU?
Dithiothreitol (DTT) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Dithiothreitol (DTT) do in cosmetics?
Dithiothreitol (DTT) functions as: Reducing agent primarily used as a laboratory reagent in protein biochemistry, not a standard cosmetic ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 3483-12-3.
What is the Margin of Safety for Dithiothreitol (DTT)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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