Ethylhexyl Acetoxystearate
INCI: ETHYLHEXYL ACETOXYSTEARATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Ethylhexyl Acetoxystearate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Minimal concern. Non-comedogenic per class data. Hydrolysis products (2-ethylhexanol and acetoxystearic acid) should be considered in cumulative 2-ethylhexanol exposure calculations, but exposure from this high-molecular-weight ester is very low.
Frequently Asked Questions
Is Ethylhexyl Acetoxystearate safe in cosmetics?
Minimal concern. Non-comedogenic per class data. Hydrolysis products (2-ethylhexanol and acetoxystearic acid) should be considered in cumulative 2-ethylhexanol exposure calculations, but exposure from this high-molecular-weight ester is very low. The EU classifies Ethylhexyl Acetoxystearate as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.
Is Ethylhexyl Acetoxystearate allowed in the EU?
Ethylhexyl Acetoxystearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethylhexyl Acetoxystearate do in cosmetics?
Ethylhexyl Acetoxystearate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 61800-40-6.
What is the Margin of Safety for Ethylhexyl Acetoxystearate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethylhexyl Acetoxystearate?
The NOAEL (No Observed Adverse Effect Level) for Ethylhexyl Acetoxystearate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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