Is Gamma-Polyglutamic Acid (γ-PGA) safe in cosmetics?
Gamma-Polyglutamic Acid (γ-PGA) has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Gamma-Polyglutamic Acid (γ-PGA)
INCI: POLYGLUTAMIC ACID
Gamma-Polyglutamic Acid (γ-PGA) (CAS 25513-46-6 (polyglutamic acid); 208106-41-6 (sodium salt)) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Humectant/Moisturizing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
CAS Number
25513-46-6 (polyglutamic acid); 208106-41-6 (sodium salt)
View industrial chemical safety profile →
Function
Skin Conditioning, Humectant/Moisturizing
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; no FDA restriction; CIR has not published a standalone monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Gamma-Polyglutamic Acid (γ-PGA).
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Gamma-Polyglutamic Acid (γ-PGA) — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Gamma-Polyglutamic Acid (γ-PGA) allowed in the EU?
Gamma-Polyglutamic Acid (γ-PGA) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Gamma-Polyglutamic Acid (γ-PGA) do in cosmetics?
Gamma-Polyglutamic Acid (γ-PGA) functions as: Skin Conditioning, Humectant/Moisturizing. It is classified as a cosmetic ingredient in our database. CAS number: 25513-46-6 (polyglutamic acid); 208106-41-6 (sodium salt).
Compliance Tools
Check Gamma-Polyglutamic Acid (γ-PGA) compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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