Regulatory Status
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Safety Data
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Expert Verdict
Phytoestrogen and endocrine disruptor concern: Biochanin A is demethylated to genistein by CYP enzymes; CPSR assessor must account for this metabolic pathway when calculating total genistein exposure against the SCCS 0.007% ceiling; phytoestrogenic activity is documented.
Frequently Asked Questions
Is Genistein Methyl Ether (Biochanin A) safe in cosmetics?
Phytoestrogen and endocrine disruptor concern: Biochanin A is demethylated to genistein by CYP enzymes; CPSR assessor must account for this metabolic pathway when calculating total genistein exposure against the SCCS 0.007% ceiling; phytoestrogenic activity is documented. The EU classifies Genistein Methyl Ether (Biochanin A) as "restricted". Safety rating: MODERATE.
Is Genistein Methyl Ether (Biochanin A) allowed in the EU?
Genistein Methyl Ether (Biochanin A) EU regulatory status: restricted. Maximum allowed concentration: 0.007%. This is based on EU Regulation 1223/2009 and its amendments.
What does Genistein Methyl Ether (Biochanin A) do in cosmetics?
Genistein Methyl Ether (Biochanin A) functions as: Humectant; skin conditioning; skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 491-80-5.
What is the Margin of Safety for Genistein Methyl Ether (Biochanin A)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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