Regulatory Status
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Safety Data
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Expert Verdict
CRITICAL: H341 — Suspected of causing genetic defects (26.9% of ECHA notifications). Causes serious eye damage (H318). No tumorigenic response in chronic dermal mouse study, but mutagenicity flag remains unresolved. Harmful to aquatic organisms with long-lasting effects. Not recommended for leave-on cosmetics without full genotoxicity battery.
Frequently Asked Questions
Is Glycidoxypropyl Trimethoxysilane safe in cosmetics?
CRITICAL: H341 — Suspected of causing genetic defects (26.9% of ECHA notifications). Causes serious eye damage (H318). No tumorigenic response in chronic dermal mouse study, but mutagenicity flag remains unresolved. Harmful to aquatic organisms with long-lasting effects. Not recommended for leave-on cosmetics without full genotoxicity battery. The EU classifies Glycidoxypropyl Trimethoxysilane as "prohibited". Safety rating: POOR.
Is Glycidoxypropyl Trimethoxysilane allowed in the EU?
Glycidoxypropyl Trimethoxysilane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycidoxypropyl Trimethoxysilane do in cosmetics?
Glycidoxypropyl Trimethoxysilane functions as: Coupling agent / adhesion promoter (primarily industrial; occasional cosmetic crosslinker use). It is classified as a cosmetic ingredient in our database. CAS number: 2530-83-8.
What is the Margin of Safety for Glycidoxypropyl Trimethoxysilane?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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