Glycine HCl

INCI: GLYCINE HCL

CAS Number
6000-43-7
Function
Buffering — controls pH of cosmetic products
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — glycine is GRAS (21 CFR §170.30); HCl salt not separately restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

pH-dependent irritation if used at high concentrations without proper buffering; no significant safety concerns at typical cosmetic use levels

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Concern Level: Low

Frequently Asked Questions

Is Glycine HCl safe in cosmetics?

pH-dependent irritation if used at high concentrations without proper buffering; no significant safety concerns at typical cosmetic use levels The EU classifies Glycine HCl as "permitted". Safety rating: EXCELLENT.

Is Glycine HCl allowed in the EU?

Glycine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycine HCl do in cosmetics?

Glycine HCl functions as: Buffering — controls pH of cosmetic products. It is classified as a cosmetic ingredient in our database. CAS number: 6000-43-7.

What is the Margin of Safety for Glycine HCl?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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