Excellent Cosmetic Ingredient NOAEL Data

Sodium Glycinate

INCI: SODIUM GLYCINATE

CAS Number
6000-44-8
Function
Skin conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR reviewed and found safe in current use concentrations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Sodium Glycinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 2000 mg/kg bw/day oral rat oral REACH

Expert Verdict

None; note that dietary glutamate/phenylalanine sensitivities do not apply at cosmetic use levels

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Concern Level: None

Frequently Asked Questions

Is Sodium Glycinate safe in cosmetics?

None; note that dietary glutamate/phenylalanine sensitivities do not apply at cosmetic use levels The EU classifies Sodium Glycinate as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.

Is Sodium Glycinate allowed in the EU?

Sodium Glycinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Glycinate do in cosmetics?

Sodium Glycinate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 6000-44-8.

What is the Margin of Safety for Sodium Glycinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Glycinate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Glycinate is 2000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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