Is Glycolide safe in cosmetics?
Glycolide has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Glycolide
INCI: GLYCOLIDE
Glycolide (CAS 502-97-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent; cyclic diester precursor of glycolic acid. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 502-97-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent; cyclic diester precursor of glycolic acid
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1,4-dioxane-2,5-dione
InChIKey
RKDVKSZUMVYZHH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no 21 CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycolide.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Glycolide.
Frequently Asked Questions
Is Glycolide allowed in the EU?
Glycolide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycolide do in cosmetics?
Glycolide functions as: Skin conditioning agent; cyclic diester precursor of glycolic acid. It is classified as a cosmetic ingredient in our database. CAS number: 502-97-6.
Compliance Tools
Check Glycolide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Is Glycolide in Your Products?
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