Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for HC Blue No. 14. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 50 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Anthraquinone-class direct dye prohibited in EU but permitted in US under coal tar hair dye exemption; mandatory allergy warning required.
Regulatory Flags
Frequently Asked Questions
Is HC Blue No. 14 safe in cosmetics?
Anthraquinone-class direct dye prohibited in EU but permitted in US under coal tar hair dye exemption; mandatory allergy warning required. The EU classifies HC Blue No. 14 as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is HC Blue No. 14 allowed in the EU?
HC Blue No. 14 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Blue No. 14 do in cosmetics?
HC Blue No. 14 functions as: Hair dyeing (anthraquinone-class direct dye). It is classified as a cosmetic ingredient in our database. CAS number: 99788-75-7.
What is the Margin of Safety for HC Blue No. 14?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for HC Blue No. 14?
The NOAEL (No Observed Adverse Effect Level) for HC Blue No. 14 is 50 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
Check HC Blue No. 14 compliance across multiple jurisdictions:
Related Ingredients
Is HC Blue No. 14 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for HC Blue No. 14 in your formulation.